🧬 Regenerative Medicine Aftercare

    P-Shot (Priapus Shot) Aftercare Instructions

    A day-by-day recovery guide for p-shot (priapus shot): what to expect, how to care for yourself, and when to call. Free to read and print.

    Typical recovery: about 14 daysRegenerative Medicine

    What to expect

    The emergency sign to act on immediately

    • •Go to the emergency department for an erection that lasts more than 4 hours or is painful (priapism). This is rare but urgent.

    P-Shot (Priapus Shot) recovery, day by day

    Day 0 (Procedure Day)

    What is normal right after

    • The P-Shot uses PRP concentrated from your own blood, so allergic reaction is very rare.
    • Mild swelling, tenderness, redness, small bruises, and a feeling of fullness are common for the first few days and settle on their own.
    • A numbing cream is used during the procedure, so some numbness may linger for a few hours. You can usually return to your normal day right away.
    Days 1 to 2

    Activity in the first 48 hours

    • Avoid strenuous exercise, heavy lifting, cycling, and prolonged sitting on hard surfaces for the first 24 to 48 hours to limit swelling.
    • Wear supportive, non-restrictive underwear. Keep the area clean and dry.
    • You may shower normally; avoid baths, hot tubs, and swimming pools for 48 hours while the tiny needle sites close.

    Sexual activity, device, and comfort

    • Follow your provider's guidance on when to resume sexual activity; many patients are cleared within 24 to 48 hours once initial tenderness settles.
    • If your provider prescribed a vacuum erection device (pump) to use during the healing window, use it exactly as they instructed. Do not use any device or supplement they did not prescribe.
    • Use acetaminophen (Tylenol) for soreness rather than NSAIDs, which can blunt a PRP result. Avoid alcohol for 24 hours.
    Days 3 to 14

    How the result develops and any series

    • Some patients notice changes within the first couple of weeks, but the PRP effect builds over 6 to 12 weeks as tissue responds.
    • The P-Shot is sometimes done as a small series or repeated periodically for maintenance; your provider will discuss whether that fits your goals at follow-up.
    • Track your response so that conversation is grounded in real change.

    Medications you may be given

    Acetaminophen (Tylenol) 500mg

    Take 1 to 2 tablets by mouth every 6 hours as needed for soreness. Do not exceed 3000mg in 24 hours. Preferred over NSAIDs, which can blunt a PRP result.

    Always follow the exact directions your own provider gives you. This is general information, not a prescription.

    When to call your provider or 911

    • •An erection that lasts more than 4 hours or is painful (priapism) - go to the emergency department
    • •Spreading redness or warmth, or significant or worsening swelling after day 2
    • •Pus or drainage, or fever over 101F
    • •Difficulty or pain with urination
    • •Pain not controlled by acetaminophen

    When in doubt, call your clinic. For a medical emergency, call 911.

    Recovery milestones

    1. Day 0

      Procedure day

      Mild swelling and tenderness expected; supportive underwear; acetaminophen only.

    2. Day 2

      Tenderness settles

      Initial soreness and swelling ease; resume activity per your provider's guidance.

    3. Day 7

      Needle sites closed

      Safe to resume baths, pools, and hot tubs; continue any prescribed device use.

    4. Day 14

      Result develops

      PRP effect building; assess with your provider and plan any follow-up.

    For clinics

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